A negative nitrogen balance can be used as part of a clinical evaluation of malnutrition.
2.
Negative nitrogen balance is associated with burns, serious tissue injuries, fevers, hyperthyroidism, wasting diseases, and during periods of fasting.
3.
Low glutathione is commonly observed in wasting and negative nitrogen balance, as seen in cancer, HIV / AIDS, sepsis, trauma, burns, and athletic overtraining.
4.
In addition to measurements relating directly to skeletal muscle strength and mass, indirect measurements were made that demonstrated that all Skylab crewmembers had a negative nitrogen balance indicative of skeletal muscle attrition.
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